There's no single cause of borderline personality disorder (BPD) and it's likely to be caused by a combination offactors.
Genetics
Genes you inherit from your parents may make you morevulnerable to developing BPD as there is evidence that the condition can run in families.
Problem with brain chemicals
It's thought that many people with BPDhave something wrong with theneurotransmitters in their brain, particularly serotonin.
Neurotransmitters are "messenger chemicals" used by your brain to transmit signals between brain cells.Altered levels of serotoninhavebeen linked to depression, aggression anddifficulty controlling destructive urges.
Problem with brain development
Researchers have usedMRI to study the brains of people with BPD. MRI scans use strong magnetic fields and radio waves to produce a detailed image of the inside of the body.
The scans revealed that in many people with BPD, 3 parts of the brain were either smaller than expected or had unusual levels of activity. These parts were:
- the amygdala–which plays an important role in regulating emotions, especially the more "negative" emotions, such as fear, aggression and anxiety
- the hippocampus–which helps regulate behaviour and self-control
- the orbitofrontal cortex–which is involved in planning and decision making
Problems with these parts of the brain may well contribute to symptoms of BPD.
The development of these parts of the brain is affected by your early upbringing. These parts of your brainare also responsible for mood regulation,which may account forsome of the problems people with BPD have in close relationships.
Environmental factors
Anumber of environmental factors seem to be common and widespread among people with BPD. These include:
- being a victim of emotional, physical or sexual abuse
- being exposed to long-term fear or distress as a child
- being neglected by 1 or both parents
- growing up with another family member who had a serious mental health condition, such asbipolar disorder or a drink or drug misuse problem
