Many stands that operate from a distance (wonder of u which I remember being an abstract concept therefore immune to overwriting) they can beat it.
Its power is based on touching things physically.
If it doesn't touch something = it doesn't overwrite
Heavy weather can beat it because ... It operates from a distance, it can turn it into a snail and Dio can no longer do anything.
It also works with the time stop.
Soft and wet has bubbles that transcend logic, they have NEP (so Dio not even can overwrite them) and influence abstract concepts could beat twoh.
GER Canon ≠ GER eoh.
GER eoh has to touch things to be able to bring them to 0, therefore it activates after / during the effects take place.
Twoh when collided with GER's fist overwrote it and canceled it because RTZ it is activated after / during the effect (= overwrite)
GER Canon activates before effects and has multiversal range.
Twoh can't hit it, so = no overwrite.
Tusk act 4 would have a chance, as long as he shoots a lot of Golden spins.
Dio he will not be able to hit them and cancel them all and he will die.